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Pharmacogenetic testing (PGx)
A simple test by which your doctor can determine which medicines and doses are right for you.
Patients whose treatment schedule comprises several drugs or whose conditions require treatment to be established through successive attempts of medication schemes need to be chosen the drug that gives the best results.
Our genes are unique, which makes us metabolize drugs differently. Certain medications can cause side effects or are not quite effective.
Currently, more than 250 prescription drugs contain pharmacogenetic information in their FDA-approved package leafle
AMS Laborator Genetic, together with Genelex, propose you PGx testing.
PGx testing can help your doctor understand how drugs interact with your genes.
Studies have shown that integrating information from pharmacogenetic testing into the drug prescribing process can help improve efficacy and reduce adverse effects.
Pharmacogenetic tests can be found in the form of general panels dedicated to different medical specialties.
All tests include a clinical care tool that helps identify potential drug-drug and / or drug-gene interactions.
Pharmacogenetic Standard Panel
CYP3A4, CYP3A5, CYP2C9, CYP2C19 and CYP2D6
Pharmacogenetic Comprehensive Panel
ADRA2A, CYP1A2, CYP3A4, CYP3A5, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP4F2 / VKORC1, COMT, DPYD, F2 (Factor II), F5 (Factor V) Leiden, GRI, IFNL3 (IL28B), MTHFR, NAT2, OPRM1, SLCO1B1, TPMT, UGT1A1
Pharmacogenetic Cardiology Panel
CYP3A4, CYP3A5, CYP2C9, CYP2C19, CYP2D6, APOE, F2 (Factor II), F5 (Factor V) Leiden, MTHFR, SLCO1B1 (statins), VKORC1 (warfin)
Pharmacogenetic Psychiatry Panel
CYP3A4, CYP3A5, CYP2C9, CYP2C19, CYP2D6, GRIK4 (citalopram), HTR2A (SSRIs, non-SSRIs), HTR2C (antipsychotics)
The analysis of the results is based on the information provided by the pharmacogenetic testing (PGx), combined with the analysis of the clinical pharmacist and the scientific data approved by the regulatory agencies in the field.
The prescribing physician benefits from a specialized clinical support platform, called YouScript. Based on current clinical evidence, YouScript is the only software that provides a biological basis for understanding why interactions occur and then informs about safer and more effective alternatives for each individual patient.